Friday, August 9, 2019

Financial Issues, Marketing Function and Human Resources in Management Essay

Financial Issues, Marketing Function and Human Resources in Management - Essay Example Organizing: Organising refers to the process of grouping the related activities and assigning them to a manager with authority to supervise it, organizing is an essential function that makes the plans operational by identifying and classifying necessary activities. 3. Staffing: Ascertain how many positions are there in the organization and at what level. Once this information is available, the next task is to collect details such as what type of candidates is required for each position, and accordingly, fill up these positions with the right people. Staffing is a process which includes recruitment, selection, training, placement, appraisal, promotion, and career planning. 4. Directing: After filling the positions in the organization with the right kind of people, the next task is to guide and enable them to achieve the common goals. It Includes;(a). Leading: It is a decisive function of the management in which the worker's employees are led and directed so that the objectives of the organization will be successfully achieved. (b). Motivating: It is one of the most important processes which are stimulating the employees to perform more effectively using their abilities and full potential. (c). Communicating: It is a process of creating, transmitting, and interpreting messages, ideas, facts, options, and feelings.(d). Coordinating: It is a process of measuring the current performance of the employee and assesses whether the given objectives are achieved or not.Now we shall discuss the issues in the management.... successfully achieved. (b). Motivating: It is one of the most important processes which are stimulating the employees to perform more effectively using their abilities and full potential. (c). Communicating: It is a process of creating, transmitting, and interpreting messages, ideas, facts, options and feelings. (d). Coordinating: It is a process of measuring the current performance of the employee and assess whether the given objectives are achieved or not. Now we shall discuss about the issues in the management which a manager should consider and study deeply when planning development, we will begin with the financial issue which should be considered first as no firm can run nicely without enough finance. Financial management is a service activity which is associated with providing quantitative information, of financial nature and that this may be needed for making economic decision regarding the choice among alternative course of actions. Financial management is that specialized function of a general management which is related to the procurement of financial and its effective Utilization for the achievement of the goal of the organization.In the past few years financial management has undergone significant changes as regards its scope and coverage. As such the role of finance manager has also undergone fundamental changes over the years. Profit maximization is not considered as basic idea for making investment and financing decision. The financial management of a firm has to make three important decisions. (1) Investment decision i.e., where the invest funds and in what amount. (2) Financing

Thursday, August 8, 2019

Literature Review - Marketing of luxury cars depending on affinity

- Marketing of luxury cars depending on affinity groups in America and The Middle East - Literature review Example In order to analyze the learning style, four vital tests have been used which are Myers-Briggs test, Belbin test, Honey & Mumford test and VARK analysis. From the analysis of Myers-Briggs test I have found that I possess the ENFJ learning style. The results of Belbin test depict that in team environment I act as plant, resource investigator and shaper. On the other hand, the Honey & Mumford test depict that I am activist and pragmatist learner. Finally outcome, of VARK analysis suggest that I prefer visual and kinaesthetic learning style. The assignment also describes about the transferrable skill I possess and how these skills can be used in my career. The discussion in Part B of the assignment elaborates on the current market trends witnessed in relation to the luxury car market around the world. Contextually, it argues that despite the rise in the demand of luxury cars across the globe, the American car market has witnessed significant fall in the production of luxury cars. Additionally, America is considered to be the home of diverse culture, owing to which, the luxury car market in the nation can be observed as significantly influenced by the Hispanic population. Hence, marketers of luxury cars have currently been involved in attracting reasonable Hispanic population towards their respective luxury car brands. On the other hand, luxury car markets in the Middle East have been flourishing at much greater speed due to the rise in the level of disposable income as well as due to the improvements in the roadway transportation facilities. The findings obtained through this study further reveals in this regard that the marketing str ategy related with luxury cars in America and the Middle East in years to come is quite likely to be strongly influenced by the affinity factor. Simultaneously, Customer Relationship Management (CRM) may also positively influence the marketing strategies of the luxury cars

Wednesday, August 7, 2019

Burn Norton (T.S. Elliot) Essay Example for Free

Burn Norton (T.S. Elliot) Essay Describe the sound and pace of the opening section of Burnt Norton, and compare those qualities to the meters and language used in section II. Why do you suppose that the first stanza of section II is a tetrameter with a rhyme scheme, while the stanzas before and after forgo rhyme and use a variety of time lengths? What might those variations suggest about the tone of the poems opening and the psychological or spiritual content? The first stanza of section II is a tetrameter with a rhyme scheme because each of its lines was composed of eight syllables, four of which are stressed or accented (eHow. com, 2009). In sharp contrast, the stanzas before and after did not adhere to this structure. They were made up of lines that appeared to be more of spoken language than verses of poetry. It would be fair to say that the stanzas before and after the first stanza of section II are free verse forms of poetry. Such a variation is not without purpose – it was intended to highlight the nostalgic and apprehensive tones of the poem’s opening. The poem’s opening was mainly about the speaker’s feelings about the concepts of time and change. He or she was torn between holding on to treasured memories of the past and submitting to the inevitable arrival of change. The spiritual content of the poem likewise reflected the aforementioned conflict. It was revealed in the end of the first stanza that although the speaker finally acknowledged the inseparability of change in all aspects of human existence, he or she did so with a heavy heart. 2. The word â€Å"time† appears over and over again in Burnt Norton. How is time invoked or described at various points in the poem? Is there an interesting progression or change in these references? What lines strike you as especially odd or mysterious? What is their effect? Singly or together? Indeed, the word â€Å"time† appears over and over again in Burnt Norton. But the speaker has diverging descriptions of time in the poem. At the beginning of the first stanza, for example, he or she invoked time as an adversary: All time is unredeemable. What might have been is an abstraction Remaining a perpetual possibility Only in a world of speculation. What might have been and what has been Point to one end, which is always present. (n. pag. ) But towards the last stanza of section V, the speaker finally realized the futility of trying to make time stop in order to maintain a cherished status quo: Desire itself is movement Not in itself desirable; Love is itself unmoving, Only the cause and end of movement, Ridiculous the waste sad time Stretching before and after. (n. pag. ). The above-mentioned insight stemmed from the fact that ideals such as love and desire were attained mainly because there were individuals who willingly abandoned convention in order to pursue them. I myself initially found these lines to be odd – the speaker suddenly changed his or her views on love and desire after agonizing about their inevitable loss for the most part of the poem. But these lines also had a single effect on me – they enlightened me on the real nature of love and happiness, as well as how they are truly attained. 3. Read the first ten lines of section V, and consider them as possible commentary on poetry – and on this poem in particular. What is suggested here about the importance of â€Å"Words, after speech† or â€Å"the form, the pattern† that can â€Å"reach/The stillness†? What inferences do you draw from these lines about what Burnt Norton is attempting to achieve? The first ten lines of section V suggested that the things which people appreciated (poetry, music, etc. ) became what they are mainly because people had the opportunity to look back and realize their value long after they had been created. A given piece of literature, for instance, can be appreciated only after it has been read or heard. A certain artwork can be judged to be of value only after its completion. The inevitable passage of time allowed people to come up with ideas on what is beautiful, ugly, good and bad. The first ten lines of section V are implying that change should be welcomed instead of shunned. The passage of time brings about change that an institution needs to survive. This change can come in the form of the discovery of new ideas, principles and beliefs. A form of music that was dismissed as scandalous a century ago could be now deemed as sophisticated. Would these be possible if time was stopped just to preserve a treasured status quo? References eHow. com. (2009). How to Write in Iambic Tetrameter. Retrieved June 16, 2009, from http://www. ehow. com/how_4392330_write-iambic-tetrameter. html Tristan. Icom43. net. (2000, June). Burnt Norton (No. 1 of â€Å"Four Quartets†). Retrieved June 16, 2009, from http://www. tristan. icom43. net/quartet

Tuesday, August 6, 2019

Gender Representation - Boardwalk Empire Essay Example for Free

Gender Representation Boardwalk Empire Essay As a hybrid genre, the representations in Boardwalk Empire are complex, contradictory, unconventional, conventional and stereotypical, whilst challenge stereotypes. Set in the 1920’s during prohibition, Nucky is a corrupt Republican politician and gangster, who has risen to his position through bribery, corruption, and murder. The series begins as prohibition begins, with Nucky toasting the government who ban alcohol; â€Å"†¦to those beautiful ignorant bastards in Washington†. As a gangster, Nucky knows he can make millions by supplying illegal alcohol to the public and is portrayed as a businessman, making money for all the ‘respectable’ local dignitaries that sit around his table; the chief of police (his brother Ely), the mayor, the head of the port authority, local Politicians, etc. He sees an opportunity through the prohibition to increase his fortune. There is a lot of juxtapositioning in the first episode to show us the various sides of Nucky, as a violent alcohol heist is followed by Nucky addressing a Ladies’ Temperance Society. Nucky weaves a myth of his own childhood of poverty, catching rats for his family to eat, to the gasps of the audience. Embodying the American Dream, Nucky has ‘risen’ from very humble beginnings to be top man in the state, he is merely seeking the ‘women’s vote’ for his Political re-election and often shows their ignorance of world politics proves them an easy mark for manipulation to gain full power over the Atlantic City. Nucky is a complex protagonist and anti-hero who is both despicable and admirable. He is obviously very clever, charming, funny, calculating, ruthless, and a skilful businessman and gangster. He juggles a legal political life with his illegal prohibition life, dealing with a constant flurry of unexpected problems as they arise. He manipulates people in ways that should make audiences hate him but Steve Buscemi (and the writers) manages to portray him as a complex character that seeks more than just money. The low camera angles throughout help suggesting Nucky is a very powerful figure in the drama. The power wield of woman in Boardwalk Empire is largely associated with sex, and furthermore this power of woman is represented through the male characters using it against eachother. For example Gillian Darmody, mother of gangster: Jimmy Darmody and a topless dancer in the city, plays a pivotal role when she sleeps with a rival gangster: Luciano in order to detain him until he can be collected and dealt with. Her sexual power is turned to the gangsters own advantage. Lucy Daziger is another key representation of sexual power and woman in Boardwalk Empire. She is the beautiful mol and mistress of Nucky who is often a negative representation of woman – dismissed constantly in favour of Nucky’s political and illegal life. She is objectified by him and others and is kept at his beck and call. During an evening at dinner with others, Lucy insists she has a brain but is quietened by Nucky, and we see Lucy has no place for opinion at the dinner with the Commodore in terms of politics. When Nucky rejects Lucy, he favours Margaret, because she is intelligent and sees her more as an equal for example at the same dinner Margaret expresses deep knowledge and understanding of politics. Lucy is extremely jealous of Margaret as Nucky clearly shows more affection for her, which is unconventional as Lucy is the beautiful mistress, often seeming powerful, Margaret is the opposite.. Margaret is the other key representation in the drama as she challenges the notion of ‘the little woman’ throughout the series. An Irish immigrant, clever, brave, and moral (but racked by guilt), her motives are often those of a protective Mother. Initially established as naive and unsophisticated, particularly by her dowdy dress codes i. colour codes are very dull: browns, greens, her deferential body-language, and her thick Irish accent, she is represented as a weak, ordinary and poor woman. For example her dress codes of poor clothing often lacking in quality, and colour. Margaret grows in confidence throughout the seasons, as her and Nucky begin a relationship. An Irish immigrant she is wise beyond her years, Margaret quickly becomes versed in the dealings of her â€Å"husba nd† and becomes a supportive and protective ‘wife’ for his chaotic life. In her previous marriage Margaret was represented in a weak and negative way enduring endless beatings from her husband Hans. An incident of abuse had caused Margaret to miscarry her 4th child, and so Nucky ordered to have Hans murdered. Margaret knows of this but chooses to remain silent for the benefit of herself and her kids, later racked with Catholic guilt over the murder, their life, and their source of income. Nucky proceeds to live with her and her children, becoming a sensitive father figure to the kids, and a loving ‘husband’ to her.

Monday, August 5, 2019

Case Study: Patient With Shortness Of Breath

Case Study: Patient With Shortness Of Breath Patient Identity The patient is a 54 year old female, Mrs SK who is a housewife with a BMI of 25.7kg/m2. Presenting Complaints She was brought in to the Accident and Emergency (AE) department, complaining of shortness of breath (SOB) and a productive cough. History of Presenting Complaints The patient was experiencing SOB for the past 2-3 days, and was progressively worsening on the day on admission. It was not associated with chest tightness and she was able to sleep the night before. She was also having persistent productive cough with white sputum since she was last discharged 12 days ago. Past Medical History She was diagnosed with diabetes mellitus and hypertension 8 years ago and has history of gastritis for the past 5 years. She was newly diagnosed with bronchial asthma in her last admission two weeks ago. Social History The patient is a widow since 6 years ago and is a housewife with 3 children. She stays in a factory area and has a cat at home. She is a non-smoker and a non-alcoholic. Family History Her mother and father have no known medical illness, but she has a cousin who suffers from bronchial asthma and is frequently admitted to the wards. Drug History The patient was on Salbutamol and Budesonide inhalers, 200mcg when necessary and 200mcg once at night respectively for her bronchial asthma. For her hypertension, she was on 40mg Telmisartan tablets once at night. She was also taking Gliclazide tablets, 80mg twice daily and Metformin tablets, 500mg three times a day for her diabetes mellitus. For her hypercholestrolaemia, the patient was taking Lovastatin tablets 20mg once at night. Based on the Morisky Scale, she was compliant with her medication and she had no known drug allergy. Examination Details On examination, the patient was alert and conscious. She was pink and appeared to be fairly hydrated. She was also able to speak in full sentences, and was not tachypnoeic. A Chest X-ray showed that there was a pneumonic consolidation at the right lower lobe of her lungs. Her blood pressure (BP) was 152/82mmHg, pulse rate (PR) was 109 beats per minute (bpm) and was afebrile. Her oxygen saturation (SpO2) was 96% under 3 litres of oxygen and her blood glucose was measured to be 4.7mmol/L. Investigations Upon admission, standard laboratory investigations were carried out and were obtained. From the renal function test, it was seen that the patient had a low potassium level of 2.8mmol/l and her calculated creatinine clearance was 60.0ml/min which indicated that she had mild renal impairment. The liver function test showed that she had normal liver function. The following shows the results that were out of the reference values for her haematological tests. C-Reactive Protein (CRP) 31.1 à ¢Ã¢â‚¬  Ã¢â‚¬Ëœ Erythrocyte Sedimentation Rate (ESR) (0 15 mm/hr) 110 à ¢Ã¢â‚¬  Ã¢â‚¬Ëœ Haemoglobin (Hb) (13.5-18 g/dl) 10.3 à ¢Ã¢â‚¬  Ã¢â‚¬Å" Haematocrit (0.36-0.46 L/l) 0.303 à ¢Ã¢â‚¬  Ã¢â‚¬Å" Red Blood Count (RBC) (3.8-4.8 x 1012 /l) 3.45 à ¢Ã¢â‚¬  Ã¢â‚¬Å" White Cell Count (WCC) (4-11 x 109 /l) 15.1 à ¢Ã¢â‚¬  Ã¢â‚¬Ëœ Neutrophil (Neutro) (2 7.5 x 109 /l) 10.57 à ¢Ã¢â‚¬  Ã¢â‚¬Ëœ Diagnosis/Impression Patient was initially diagnosed with Acute Exacerbation of Bronchial Asthma (AEBA) secondary to an upper respiratory infection (URTI) to rule out pneumonia. However, later in the day when the chest X-ray came back, she was diagnosed with pneumonia with right parapneumonic effusion. Management Plan The patients current medication was continued and was given 3 litres of oxygen via a nasal prong (NP). She was commenced on prednisolone tablets, 30mg once a day and was given nebulised Combivent (Ipratropium 20mcg/salbutamol 100mcg), every 4 hours. Her peak expiratory flow rate (PEFR) and SpO2 was to be monitored. Antibiotics were kept in view to be started if necessary after the total white blood count results came back. Clinical Progress Upon admission, the patient was afebrile, was tolerating orally well, did not have any sorethroat but was having a non productive cough. An echocardiogram (ECG) was done and it showed that she had sinus rhythm with no ischaemic changes. As her chest x-ray showed a right lower zone consolidation, she was diagnosed with pneumonia. She was immediately commenced on 2g Ceftazidime intravenously, and then continued on 1g three times a day. She was also under nebulised combivent every 6 hours. Her metformin and gliclazide was stopped and she was started on subcutaneous 10 units of Humulin  ® three times a day and 12 units of Humulin N once at night. On Day 2 of her stay, her blood results came back and as she has low potassium levels, she was given 15mls of Mist KCl three times daily and two Slow K tablets once daily. She was still complaining of cough without sputum and was given 15mls of Benadryl (diphenhydramine) syrup three times a day. The patient did not have any major complaints on the third day and was tolerating orally well. There was no SOB seen and she had good inhaler technique. She was then taken off the nebulizer combivent and the oxygen. By day 4, the patient was comfortable, and her cough and sputum had decreased. Examination on her lungs showed that she had prolonged expiratory phase. She was stopped on the Benadryl as well as Mist KCl and Slow K. After reinforcement on the inhaler technique by the pharmacist, the patient was discharged on day 5 as she was afebrile and had minimal cough. On discharge, she was then switched back to her oral hypoglycaemics and her intravenous antibiotic was switched to oral Cefuroxime 500mg twice daily for the next 10 days. She was also given Neulin SR 250mg once at night. Table 1 shows the vital signs chart for Mrs SK throughout her hospital stay. Table 1: Vital Signs Chart Day Time BP (mmHg) PR (bpm) SpO2 Blood Glucose (mmol/l) 1 13.00 178/102 109 100% 6.9 14.00 152/82 109 98% à ¢Ã¢â‚¬  Ã¢â‚¬Å" NP 15.40 4.7 18.40 133/73 114 97% à ¢Ã¢â‚¬  Ã¢â‚¬Å" RA 21.15 6.2 23.05 151/82 119 2 03.15 143/81 106 06.00 6.3 08.30 119/67 94 100% 10.35 4.8 11.24 100/61 107 97% 15.20 112/82 100 16.30 128/70 100 6.2 22.00 3.6 23.50 118/59 66 98%à ¢Ã¢â‚¬  Ã¢â‚¬Å"3L O2 3 04.10 124/64 104 100%à ¢Ã¢â‚¬  Ã¢â‚¬Å"3L O2 06.15 8.2 09.40 100/60 96 11.50 8.5 15.30 108/67 94 17.20 7.4 20.00 121/75 86 4 04.00 110/56 62 06.00 7.9 08.00 110/70 63 4.2 16.00 105/75 91 96% 17.00 9.7 22.00 138/67 114 6.1 5 05.00 9.6 07.15 11.1 Pharmaceutical Care Issues The first care issue is to review the management of AEBA based on the British Guideline on the Management of Asthma. The dose of prednisolone should be increased to 50mg once a day for at least 5 days or until recovery. Since the patient is prescribed with theophylline on discharge, she should be counseled on the signs and symptoms of theophylline toxicity such as confusion, dizziness, diarrhoea, nausea, fatigue and headache. The second issue is regarding the choice of antibiotics for the treatment of community acquired pneumonia in this patient. A sputum full examination microscopic examination (FEME) should be requested to identify the causative microorganisms of the lung infection. If empirical treatment is to be started the preferred drugs of choice would be amoxicillin 500mg three times a day plus either erythromycin 500mg four times a day or clarithromycin 500mg twice daily. Alternative choices would be levofloxacin 500mg once daily or moxifloxacin 400mg once a day, should the patient be intolerant of the preferred regimen. Thirdly, there is no clear indication of the prescription of the diphenhydramine in the first place, as it would only suppress the patients cough, which is inappropriate. Hence it should be stopped immediately. Next, the patients updated blood cholesterol levels should be taken and the appropriate use of statins should be reviewed. As she is on long-term statin use, her liver enzymes should be monitored regularly and if is raised by three-fold, she should stop taking the Lovastatin. She should also be counseled on the symptoms of rhabdomyolysis which is related to the long term use of statins, such as unexplained muscle pain, stiffness, weakness and the darkening of urine colour. The following issue is regarding the patients diabetes management. A HbA1c test should be done to determine her glycated haemoglobin level to see how well her self-management has been. She should also be advised on diet and lifestyle to keep her diabetes under control. Lastly, as she has low red blood count, haemoglobin and haematocrit levels, it is suspected that she has anaemia. Further tests should be done to confirm this, and if it is diagnosed, she should be given ferrous supplements such as ferrous sulphate tablets 200mg twice daily. DISEASE OVERVIEW AND PHARMACOLOGICAL BASIS OF DRUG THERAPY Acute Exacerbation of Bronchial Asthma: An Overview Asthma is a chronic inflammatory disorder of the airways where many cells and cellular elements play a role. This leads to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night or in the morning. These inflammatory symptoms are commonly associated with extensive but variable airflow obstruction within the lung as well as airway hyperresponsiveness and this is reversible either on its own or with treatment. 1 Asthma is a worldwide problem as it is estimated that about 4.5% of the worlds population is affected, which amounts to 300million individuals approximately. The global prevalence of asthma varies from 1-18% of populations in countries all over the world. Asthma has three distinguishing characteristics which are airflow limitation, airway hyperresponsiveness, and bronchial inflammation. Airflow limitation is usually resolved by itself with or without treatment but for individuals with chronic asthma, inflammation may result in irreversible airflow limitation. Stimuli such as irritants or allergens may pose as triggers in airway hyperresponsiveness and bronchial inflammation is associated with eosinophils, T-lymphocytes and mast cells which cause plasma exudation, smooth muscle hypertrophy, mucous plugging and epithelial changes. It is shown that inflammation of the airways play a major role in the pathology of asthma and this starts when allergens or irritant trigger the activation of cells such as epithelial cells, macrophages, lymphocytes and mast cells. This leads to cytokine or mediator release and smooth muscle contraction resulting in cellular infiltration of eosinophils and neutrophils causing airway inflammation including oede ma, epithelial permeability or injury, mucous secretion and vascular permeability which eventually leads to airway obstruction and hyperresponsiveness. The diagnosis of asthma is based on a collection of signs and symptoms without a reasonable explanation for them and spirometry is an early test which is easy to assess if there is any airflow obstruction present and its extent. For diagnosed patients with asthma, acute exacerbations may occur and because patients with severe asthma are at increased risk of death following exacerbations, assessments of exacerbations are crucial. Clinical features of acute asthma exacerbations include severe breathlessness, tachypnoea, tachycardia, silent chest, cyanosis, or syncope. Peak Expiratory Flow (PEF) or Forced Expiratory Volume in one second (FEV1) is also used to measure the lung capacity. Oxygen saturation (SpO2) is measured using a pulse oximetry and this aids oxygen therapy as oxygen therapy is given in order to keep SpO2 levels at 94-98%. Measurements of arterial blood gases (ABG) are usually not necessary unless patients present with features of life-threatening asthma or have SpO2 of less than 92% as there may be a risk of hypercapnea if SpO2 is lower than 92%. Chest X-rays are also not recommended unless patients are suspected of pneumonia or lung consolidations, suffering from life-threatening asthma, having unsatisfactory response to treatment or if they require ventilation. Pharmacological Intervention in the management of AEBA2 Oxygen Oxygen therapy is needed most of the time as patients who are having acute asthma usually present with hypoxia as well. Hence, all patients with hypoxia who are suffering from acute severe asthma should be given oxygen and their SpO2 levels should be kept at 94-98%. ÃŽÂ ²2 agonist bronchodilators As first line therapy, high dose inhaled ÃŽÂ ²2 agonist bronchodilators are used as soon as possible as rapid relievers of bronchospasm. For patients who are unable to use inhaled therapy, intravenous ÃŽÂ ²2-agonists are used instead. ÃŽÂ ²2 agonist bronchodilators work by stimulating the ÃŽÂ ²2 adrenoceptors in the lungs, thus causing relaxation of the airways. Examples of short acting ÃŽÂ ²2-agonist are salbutamol and terbutaline, and a long acting ÃŽÂ ²2-agonist is salmeterol. Glucocorticosteroids Steroids should always be given in all cases of acute asthma. Examples of these are prednisone, prednisolone, dexamethasone, and hydrocortisone. They exert an anti-inflammatory effect by inhibiting transcription of the genes for the cytokines implicated in asthmatic inflammation and hence reduce airway hyper-responsiveness. Anti-cholinergic agents Ipratropium bromide is one of the anti-cholinergic agents that is used widely in treatment of acute exacerbations of asthma. Nebulised ipratropium bromide is used in combination with a ÃŽÂ ²2-agonist bronchodilator as treatment for patients with severe acute or life-threatening asthma. Anti-cholinergic agents work by inhibit muscarinic receptors M1 and M3 which then reduces cGMP formation and decreases smooth muscle contractility in the lungs. This eventually results in bronchodilation and reduces mucus secretion. Other therapies Other therapies include the use of magnesium sulphate. A single bolus dose of intravenous magnesium sulphate is administered to patients with acute severe asthma with previous unsatisfactory response to inhaled bronchodilator therapy or for patients who are suffering from life-threatening or near fatal asthma. It is believed that magnesium sulphate works by reducing calcium uptake by the bronchial smooth muscle cells, causing bronchodilation and also inhibits mast cells degranulation, thus reducing the release of inflammatory mediators such as histamines, and leukotrienes. EVIDENCE FOR TREATMENT OF THE CONDITION The management of asthma can be divided into two parts; acute treatment, and long term management. Management of acute asthma It has been shown that most patients suffering from acute severe asthma are hypoxaemic. Therefore it is essential that supplementary oxygen therapy be given to them.3-6 This is administered via a face mask or nasal prong with the patients SpO2 kept between 94-98%.7 Where nebulisers are needed in therapy, oxygen-driven nebulisers are favoured instead of those that are air-driven due to oxygen desaturation when driven by air alone.8-10 However, the lack of provision of supplemental oxygen should not pose as a factor in omitting nebulised therapy from administration if deemed appropriate.11 Referring to the case presented above, the patient was treated accordingly as she was immediately given supplemental oxygen and her SpO2 was maintained well above 96% throughout hospital stay. As acute asthma is associated with symptoms of bronchospasms such as wheezing and tachypnoea, the main aim of treatment is to quickly resolve these symptoms and most often, high doses of inhaled ÃŽÂ ²2 agonist bronchodilators are effective with minimum adverse effects.12-14 Salbutamol is usually the drug of choice although there is no significant differences in terms of efficacy as compared to Terbutaline. It is shown that there are no significant clinical benefits by using a non-selective ÃŽÂ ²2 agonist such as epinephrine instead of selective ÃŽÂ ²2 agonists.15 Based on a meta-analysis, it is seen that ÃŽÂ ²2 agonists administered via inhalation are more preferable and has similar efficacy with those administered intravenously in adult acute asthma.16 In ventilated patients or those in life-threatening conditions, parenteral ÃŽÂ ²2 agonists may be added to inhaled ÃŽÂ ²2 agonist treatment although there is little evidence supporting this treatment. Although a sing le bolus nebulisation may relieve most acute asthma cases, it is shown that continuous nebulised treatment of ÃŽÂ ²2 agonists is more effective in relieving acute asthma for those with unsatisfactory response to initial therapy.17, 18 Steroid therapy is always given in acute exacerbations of asthma and it is proven that it has better result if given earlier. It not only reduces mortality but it also reduces relapses and the number of hospital admissions as well.19, 20 Oral steroids given are seen to be equally as effective as parenteral treatment hence there is no need for the use of parenteral administration of steroids unless the patient is unable to tolerate orally.19 Prednisolone 40-50mg is given daily for at least five days or until recovery and this can be stopped abruptly after the patient has recovered.2 As long as the patient is on inhaled steroids, there is no need for the dose to be tapered down slowly prior to discontinuation.21 In the case presented, the patient was commenced on steroid therapy but was under-treated as she was only given prednisolone 30mg once daily for just one day. Hence, there is a need to increase the dose of prednisolone to 50mg and to continue is for at least another four days or until recovery before stopping this treatment. In hospital therapy, anticholinergic treatments are given to severe exacerbations of asthma and nebulised ipratropium bromide is always the drug of choice used in clinical settings. A combination of nebulised ipratropum bromide with a ÃŽÂ ²2 agonist bronchodilator is often given as treatment as it is proven that a combination of these two agents has a significant increase in bronchodilatation as compared to the use of a ÃŽÂ ²2 agonist alone. Hence, there is faster recovery and will reduce the length of hospital stay. However, it is also seen that anticholinergic treatment is not particularly effective and favourable for cases of mild exacerbations of asthma as well as after the patient has been stabilized, thus is not necessary in these cases.22-24 The patient in this case was seen to be having a mild exacerbation of acute asthma and hence nebulised ipratropium bromide treatment was not necessary. However, the use of nebulised Combivent, a combination of ipratropium bromide and salbutamol was justified since this patient was re-attending with a relapse and she was also suffering from pneumonia as well. Hence, there was probably a need for a quicker rate of bronchodilation as well as faster recovery for her. The use of magnesium sulphate in hospital treatment of AEBA is not widely seen, however there have been some evidence showing the bronchodilating effects of magnesium sulphate when used in adults.25 There are also studies which report that nebulised magnesium sulphate combined with a ÃŽÂ ²2 agonist shows positive outcomes and good clinical effectiveness in hospital settings.26, 27 The use of an intravenous bolus administration of magnesium sulphate is believed to promote lung function in patients who have severe asthma without harmful side effects.28 Nevertheless, there have been no studies on the repeated administrations of magnesium sulphate, though it is presumed that repeated use may lead to hypermagnesaemia, causing muscle weakness and respiratory failure. As further extensive studies need to be done to determine the most suitable route and dosing of magnesium sulphate, this treatment is reserved only for patients with acute severe asthma without satisfactory response to inha led bronchodilator therapy and patients with life-threatening of near fatal asthma. Monitoring should be carried out constantly throughout hospital stay and in acute asthma cases, monitoring of PEF is crucial. PEF readings should be measured and recorded every 30 minutes after treatment has been started. PEF should also be monitored pre- and post- nebulisation therapies as long as the patient is in hospital and until the asthma is well under control after discharge. It is seen that after hospital discharge, a relative amount of patients either experience relapse or are readmitted into the hospital with at least 15% within two weeks following discharge.29 Therefore it is essential that patient education such as proper inhaler technique, and well-documented PEF recordings with action plans depending on symptoms experienced should be instilled in order to reduce rate of relapses as well as minimize problems associated with exacerbations after discharge.30 Monitoring of the patients PEF was done consistently throughout her hospital stay and the patient was given sufficient counseling prior to discharge on her inhaler technique. However, there was no evidence that the patient was educated on self-documenting PEF recordings as well as action plans based on symptoms experienced following discharge and this should be done in this case to avoid another exacerbation of her condition. Long Term Management of Asthma The aim of management of asthma is to keep it well-controlled without the need of rescue medications, asymptomatic, no exacerbations, no hindrance to daily activities including exercise as well as normal lung function. A stepwise management approach is adopted for asthma patients and this is to acquire initial control and maintain it by stepping up treatment to improve control if necessary or stepping down treatment if there is good control over the condition to maintain the lowest step that will control the patients condition. As the patient is currently on regular preventer therapy with inhaled steroids, she is currently on step 2 of the management of asthma. There have been many studies being carried out to compare the different inhaled steroids that are being used for asthma and it is shown that beclomethasone diproprionate and budesonide are both similarly clinically effective although there may be different devices for delivery. It has also been seen that fluticasone and mometasone being administered at half the dosage of beclomethasone and budesonide shows equivalent clinical effectiveness, however there is somewhat inadequate evidence that fluticasone possesses fewer side effects and further studies need to be carried out on establishing the safety profile of mometasone.31 A new inhaled steroid has been introduced which is ciclesonide and clinical trials have shown evidence that it has more local activity than systemic and less oropharyngeal side effects as compared to the regular inhaled steroids.3 2-35 Although this seems promising, this clinical advantage is still controversial as its safety to efficacy ratio has yet to be established and compared with the conventional inhaled steroids. Inhaled steroids are recommended as preventer drug therapy for adults as they are most clinically effective in controlling asthma based on the treatment goals outlined.36-39 The frequency of dosing of inhaled steroids are generally twice daily and it is shown that there is slight clinical benefit obtained when taken twice a day than once daily, however a once daily dosing may suffice for those with milder asthma. There is also limited evidence of advantage with increased frequency of greater than twice a day.37 In addition to that, starting at higher than recommended doses have no significant effectiveness in management of mild to moderate asthma.40 Hence the recommended dosage for inhaled steroids would be 200-800mcg daily. This would be an add-on therapy to the step 1 management of using in haled short acting ÃŽÂ ²2 agonist bronchodilator as required. Based on the presented case, the patient was on budesonide 200mcg once at night prior to admission but this was immediately increased on admission and was in line with the recommended guidelines as she was continued on budesonide 400mcg twice a day together with salbutamol 200mcg as required following discharge. Other preventer therapies may be included for the patient despite inhaled steroids being the first choice of drugs for preventer therapy. These alternatives are less effective although they have shown some clinical benefit in patients who are on short acting ÃŽÂ ²2 agonists only. Chromones which act as mast cell stabilizers such as sodium cromoglicate and nedocromil sodium have shown to be beneficial in adults.41, 42 Apart from that, leukotriene receptor antagonists montelukast and zafirlukast too have clinical benefits.37, 43, 44 Theophylline also have some evidence in showing benefits in adults.36, 45 The patient in the case presented above was prescribed sustained-release theophylline on the last day of admission. Although it is another option that may be added to daily controller medications for step 2 management, there is very little evidence on the clinical efficacy of it as a long term controller. There is no reason to justify the use of theophylline in this case as the patient is responsive and can be controlled on inhaled steroids. Further more, theophylline has a narrow therapeutic index and close monitoring of plasma theophylline levels is necessary because at concentrations above 25 µg/ml, there is high risk of tachycardia and seizures may occur if concentrations exceed 35 µg/ml. CONCLUSION After reviewing the management of the patients condition throughout hospital stay, it can be concluded that SK was treated adequately based on the current guidelines and evidences attainable. She was given all necessary treatment at point of admission and there was no lacking of medications in all four days of her hospital admission. Apart from that, monitoring of her condition was carried out consistently and all data was updated, leaving no room for questioning and doubt. However, there were a few issues that came to attention which were the prescribing of several drugs that were unnecessary such as diphenhydramine and theophylline. There were little and no clear evidence that these drugs prescribed would be of benefit to the patient, and may also increase the risk of harmful effects to her as well. Alongside treatment of her acute condition, SKs controller medications were reviewed and subsequent changes were made as appropriate. Besides that, her other co-morbidities were also managed well as treatments for her hypertension and diabetes mellitus were given accordingly. PATIENT MEDICATION PROFILE PATIENT DETAILS Name S.K. Consultant Dr YKS General Practitioner Address Gender Female Weight 65kg Height 1.59m Community Pharmacist Date of Birth (Age) 54 years old Known Sensitivities NKDA Social History Widow of 6 years, Housewife, Non-smoker, Does not drink PATIENT HOSPITAL STAY Presenting complaint in primary care / reason for admission Admission date 17/04/09 Shortness of breath for the past two days, progressively Discharge Date Discharged to 21/04/09 Home worsening today and productive cough. RELEVANT MEDICAL HISTORY RELEVANT DRUG HISTORY Date Problem Description Date Medication Comments 2001 Diabetes Mellitus T. Diamicron 80mg BD 2001 Hypertension T. Metformin 500mg TDS 2004 Gastritis T. Telmisartan 40mg ON 2009 Bronchial Asthma MDI Salbutamol 200mcg PRN MDI Budesonide 200mcg ON T. Lovastatin 20mg ON RELEVANT NON DRUG TREATMENT Prescribed Medication Start Stop Clinical/Laboratory Tests Date Result 1 T. Telmisartan 40mg OD 18/04 21/04 2 T. Gliclazide 80mg BD 17/04 17/04 3 T. Metformin 500mg TDS 17/04 4 T. Lovastatin 20mg ON 17/04 19/04 5 MDI Salbutamol 200mcg 2 puffs PRN 17/04 6 MDI Budesonide 200mcg 2 puffs BD 17/04 7 T. Prednisolone 30mg OD 17/04 17/04 8 Neb. Combivent 6-hourly 17/04 19/04 9 IV Ceftazidime 2g STAT, then 1g TDS 17/04 21/04 10 S/C Humulin R 10units TDS 17/04 21/04 11 S/C Humulin N 12units ON 17/04 21/04 12 Syrup Diphenhydramine 15mls TDS 18/04 20/04 13 T. Slow K 2tabs BD 18/04 20/04 14 Mist KCl 15mls TDS 18/04 20/04 15 T. Theophylline 250mg OD 20/04 CLINCIAL MANAGEMENT Diagn

Sunday, August 4, 2019

Natural Family Planning :: essays research papers fc

The Natural Failure of Planning   Ã‚  Ã‚  Ã‚  Ã‚  Are modern forms of contraception naturally and morally wrong? Pope Paul VI and his Humanae Vitae declare that technological methods of birth control are immoral and should not be practiced by Catholics. However, as our modern society illustrates everyday, this opinion is inappropriate for not only the faithful of the Roman Catholic Church, but also for non-Catholics. According to Munich Archbishop Cardinal Julius Doepfner, â€Å"Contraception is not intrinsically evil† (The Politics of Sex and Religion). There is a fine line the Catholic church draws between â€Å"natural† methods of family planning and the â€Å"immoral† methods of modern technology. After close review of Catholic doctrines, it is clear that this line does not exist. The intentions behind the actions are what matters. Therefore the encyclical of Paul VI , while maintaining good intentions, cannot give Catholics and non-Catholics alike complete guidance in complete humanness when it comes to contraception.   Ã‚  Ã‚  Ã‚  Ã‚  The major problem for the married believers in the Catholic faith is that Human Vitae neglects their ability to make moral decisions. Paul VI claims that contraception limits a person’s human totality and integrity. However, the reality is that the Church is limiting this principle of human existence by assuming the common man is incapable of making the correct moral choice. For example Paul VI states , â€Å"†¦how wide and easy a road would thus be opened up towards conjugal infidelity and the general lowering of morality.† (Human Vitae 8). It is absurd to believe that all moral problems in our society can be attributed to the introduction of birth control methods. Man, in his complete integrity and totality, is capable of judging moral from immoral regardless of the technological devices he is surrounded by. If all parts of a human are in harmony, means of contraception cannot invade this person’s complete humanness.   Ã‚  Ã‚  Ã‚  Ã‚  Scientific research shows that almost all practicing Catholics today believe that modern means of contraception does not interfere with their beliefs and morals. According to one study, â€Å"Even among married Catholic women who attend church every week, less than 4% use church-approved family planning methods-about the same as the total population.† (Catholics for Contraception). This illustrates the fact that people of faith have made their own interpretations of God’s desires and find no difference between natural family planning and modern methods of contraception. Weekly patrons of the church know the moral teachings of the Church and the consequences, yet the facts show that all believers have not come to a consensus.

Kants Moral Principles Essay -- Kant Immanuel Philosophy Morals Essay

Kant's Moral Principles   Ã‚  Ã‚  Ã‚  Ã‚  In the Foundation of the Metaphysics of Morals, the author, Immanuel Kant, tries to form a base by rejecting all ethical theories that are connected to consequences, and then focusing on our ethical motivations and actions. Kant wants to derive good characters out of contingently right actions. He believes that everything is contingent (everything can have good or bad worth, depending on how it is used). So he is trying to find the supreme principal of morality in all his reasoning. Kant also believes that an action is right or wrong based solely on the reason by which it was performed. However, a Utilitarian, like John Mill, would reject Kant’s reasoning of originating good characters out of actions alone, and instead argue that if an action has bad consequences, then the action was morally wrong.   Ã‚  Ã‚  Ã‚  Ã‚  Kant believes that an action has moral worth only if it is done out of respect for our moral code. He names this moral action a ‘duty.’ Kant also believes that in determining the moral worth of an action, we need to look at the maxim by which it was performed. So, we need to look at one’s reason for doing an action to determine if it is a duty. If the reason for performing the action is justified, then the action is a duty. However, Kant says there are two different types of reasons for performing an action. Kant calls these reasons ‘imperatives.’ The first reason for performing an action, the hypothetical imperative, is based on consequences and on our personal preferences. They are also contingent, meaning that they can be good or bad depending on how they are used. People choose to perform a given action because of the hypothetical imperative. The second reason for performing an action according to Kant is called the categorical imperative. These are not based on our preferences, don’t deal with consequences of an action, and are derived a priori. They are completely separate from hypothetical imperatives. We all have knowledge of categorical imperatives before experiencing them first. They are kind of a second nature for us, which needs to be recognized according to Kant. These are the most important reason for performing an action. These imperatives also have the characteristics that Kant needs in order to make his point that all of our moral principals are categ orical, have absolute authority, and are independent o... ...t hope to predict the outcome of any given situation. It is impossible; there is no such thing as seeing the future. So by making a false promise to your friend, you have still done the morally wrong action, even though it will most likely save them some suffering. It did indeed take away their choices, so they can’t act in a way they want to act (going to class). I happen to agree with Kant’s idea here. I think that no matter what the consequences are, performing the right action is always the right thing to do.   Ã‚  Ã‚  Ã‚  Ã‚  Overall I think that Kant has better arguments because they are directed at the individual, not at society in whole. I also agree that the moral worth of actions is determined by the motivating principal of the action, not by the consequences, like John Mill. So I am a deontologist, for the most part. However, I also agree with some of the things that Mill has to say. So is there a way that we can combine the ideas of Mill and Kant together in order to form a perfect society in which everybody is happy? I don’t know the answer to this question, but we should all strive to do so, and we should start by respecting each other’s autonomy and treating others as ends.